NORTRIPTYLINE

Drug Name

Nortriptyline (Nortriptyline Hydrochloride)

Common use

Nortriptyline is a medication used to treat depression. It's a tricyclic antidepressant. It increases the activity of certain chemicals in the brain that help elevate mood. Also it can be used for other purposes.

Dosage and directions

Take it by mouth with or without food.

Drug interactions

The following medications can interact with Nortriptyline: barbiturates (phenobarbital) or phenytoin, anticholinergics (benztropine), carbamazepine, chlorpropamide, or sympathomimetics (phenylephrine), azole antifungals (fluconazole), cimetidine, duloxetine, flecainide, methylphenidate, mibefradil, phenothiazines (chlorpromazine), propafenone, quinidine, selective serotonin reuptake inhibitors (SSRIs) (fluoxetine), or terbinafine, arsenic, astemizole, droperidol, furazolidone, MAOIs (phenelzine), pimozide, quinolone antibiotics (ciprofloxacin), streptogramins (dalfopristin), terfenadine, or tramadol, clonidine, guanethidine, or guanfacine, anticholinergics (benztropine), carbamazepine, chlorpropamide, or sympathomimetics (phenylephrine).

Missed dose

If you miss a dose of Nortriptyline, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you take 1 dose daily at bedtime, do not take the missed dose the next morning.

Overdose

Symptoms of overdose are agitation; bluish skin or mucous membranes; breathing problems; chest pain; coma; confusion; dry mouth; loss of consciousness; restlessness; severe drowsiness; enlarged pupils; rigid muscles; seizures; excess sweating; fainting; fast or irregular heartbeat; flushing; in-coordination; involuntary movements; shock; stupor; trouble breathing; vomiting.

Storage

Store at room temperature, between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep it out of the reach of children and away from pets.