COLOSPA

Drug Name

Colospa (Mebeverine)

Drug Uses

Colospa acts directly on the smooth muscle in the gut causing it to relax. It also prevents nerve signals getting through to the muscle in the intestines. This also causes the muscle to relax, preventing painful muscle spasm. Little or no antispasmodic effect was seen on the uterus and the bronchial muscles. Gastric emptying time and intestinal propulsion were affected much less than by papaverine. No significant inhibition of normal peristalsis has been observed.

Primary irritable colon characterised by persistent diarrhoea, alternating constipation and diarrhoea, abdominal pain and postprandial distension. Secondary irritable colon due to organic lesions such as regional enteritis, diverticulitis, specific and non-specific inflammatory conditions of the gastro-intestinal tract.

How to use

135 mg Colospa hydrochloride (1 tablet) 3 times daily, preferably before meals. After a period of a few weeks when the desired effect has been obtained, the dosage may be gradually reduced.

As atropine-like effects are absent, Colospa 135 mg is not contra-indicated in patients with glaucoma or prostatic hypertrophy.

Store in a dry, dark place, at temperatures not exceeding 30A?A°C. Keep out of reach of children.

Drug Class and Mechanism

Colospa is a musculotropic antispasmodic drug without atropic side-effects whose major therapeutic role is in the treatment of irritable bowel syndrome. It is also indicated for treatment of gastrointestinal spasm secondary to organic disorder.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Storage

Store this medicine at room temperature in a tightly-closed container, away from heat and light.