ABILIFY

Drug Title

Abilify (Aripiprazole)

Usage indications

Abilify is an add-on employed for depressive disorder, schizophrenia, manic and mixed episodes associated with bipolar disorder treatment for all age groups. This drug is used as well for the treatment of irritations due to autistic disorder. Abilify mechanism of working is unknown. It presents partial agonism at the D2 receptor, partial agonism at the 5-HT1A receptor together with antagonist profile at the 5-HT2A receptor. It is related in some way to histamine and alpha adrenergic receptors and has some relation to cholinergic muscarinic receptors.

Application mode

Use Abilify once a day during or before meal. Common initial dose makes 10 or 15 mg and can be increased afterwards in case of necessity.

Missed dose

Abilify should be taken once a day, so remember to take missed dose asap. Avoid the missed dose if you remembered about it within 12 hours and return to your usual schedule. Double dosage intake is prohibited.

Overdosage

General  serious side effects: vomiting, somnolence, and tremor, acidosis, aggression,  increased aspartate aminotransferase , atrial fibrillation, bradycardia, coma, confusion, convulsion, increased blood creatine phosphokinase, depression, hypertension, hypokalemia, hypotension, lethargy, loss of consciousness, QRS and QT  prolonged complex, pneumonia aspiration, respiratory arrest, status epilepticus, and tachycardia.

Keeping

Store at room temperature in a tightly closed dry container and keep away from children and pets. Avoid using after expiration term.